People with the highest fitness levels are less likely to develop hypertension, according to new research in the Journal of the American Heart Association.

“If you’re exercising and you’re fit, your chances of developing hypertension are much less than someone else who has the same characteristics but isn’t fit,” said Mouaz H. Al-Mallah, M.D., senior author of the study and a cardiologist at the Henry Ford Heart and Vascular Institute in Detroit, Michigan. “Increasing exercise and fitness levels probably protects against many diseases.”

More than 57,000 participants in the Henry Ford Exercise Testing Project (The FIT Project) in 1991-2009 were referred for a treadmill stress test because they experienced chest pain or shortness of breath or to rule out ischemia.

Researchers measured the participants’ physical fitness by calculating how much energy they burned in metabolic equivalents (METs), an estimate of the amount of oxygen the body uses per kilogram of body weight per minute. One MET is the amount of energy expended at rest; anything above that represents a level of exertion. High-intensity workouts translate to more METs.